Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Description: Plant extract obtained from the peony (Paeonia Lactiflora root), a flower associated with well-being and rejuvenation.The active ingredient is peoniflorin. The ethanol extract of the paeonia root as well as its major active components including gallic acid and methyl gallate were evaluated for their protective effects against free radical generation and lipid peroxidation. Zhang, Chin. EU/UK Privacy Policy Luo, A. Li, X. Yang, X. Xiao, R. Hu, T.-W. Wang, X.-Y. Skeletal muscle tissues were analysed by RNAseq, real-time quantitative reverse transcription PCR, western blotting, and immunofluorescence microscopy. [17] C.-H. Ko, C.-P. Huang, Y.-W. Lin, C.-L. Hsieh, Iran. * These statements have not been evaluated by the Food and Drug Administration. medical disclaimer HHS Xu, Neurochem. Mao, Z. Huang, Neurosci. (http://www.theplantlist.org), a member of the peony family (Paeoniaceae), and has been traditionally used in many Asian countries including China, Korea, Japan, Taiwan, and Thailand for the treatment of diverse inflammatory diseases such as rheumatoid arthritis, hepatitis, and systemic lupus erythematosus (He and Dai, 2011). Zhong Xi Yi Jie He Za Zhi 1990;10:101-2, 70. . It grows in many parts of the world, though, including China, Mongolia, and Siberia. Chin. Japanese Herbal Medicine Ninjinyoeito Mediates Its Orexigenic Properties Partially by Activating Orexin 1 Receptors. Cheng, B.-Z. Jin, L. Xiao, X.-Z. This study aimed to assess the effects of an ethanolic extract of Radix Paeoniae (RP) on cancer cachexia and elucidate its mechanism of action. White Peony Extract, aka paeonia lactiflora root extract, with paeoniflorin as the active ingredient for healthy immune function. Liu, K.-Q. [21] H.-R. Zhang, J.-H. Peng, X.-B. eCollection 2020. Pharmacol. 2020 The dried root of Paeonia lactiflora Pall. Dou, D.-J. 2019 Oct 23:112337. doi: 10.1016/j.jep.2019.112337. White peony root extract is Non-GMO and Vegan. Mao, J. Yang, Y.-P. Yang, S. Liu, L.-F. Hu, C.-F. Liu, Neurochem. Hu, W.-M. Qu, J.-F. Chen, N.-N. Cheng, Z.-L. Huang, Psychopharmacology 233 (2016) 281–293. Other Concerns Functions About the Chemical Synonyms not reported and skin conditioning Paeonia Albiflora Root Extract is an extract of the roots of the peony, Paeonia albiflora. USA.gov. Please enable it to take advantage of the complete set of features! Zhu, Br. Sun, Y.-J. Wang Y, Ma R. [Effect of an extract of Paeonia lactiflora on the blood coagulative and fibrinolytic enzymes]. 41 (2016) 2923–2936. In lung and colon cancer-bearing mice, RP significantly restored food intake and muscle mass, along with muscle function measured by grip strength and treadmill running time. Lett. About 24% of these are Herbal Extract, 0% are Other Extracts. Med. 8 (2015) 5103–5111. Rep. 9 (2019) 18469. Molecular mechanisms of cancer cachexia‑induced muscle atrophy (Review). Alibaba.com offers 757 paeonia lactiflora products. 356 (2016) 64–73. [5] F.-M. Qiu, X.-M. Zhong, Q.-Q. J. Pharmacol. White peony root extract is standardized to contain not less than 10% paeoniflorin, since this compound is the most researched of white peony root’s unique compounds and is used as the marker compound for standardization. A cotton material is soaked in a soaking liquid containing an extract from peony (scientific name: Paeonia lactiflora) having high antimicrobial and deodorizing effects among those derived from plants, and heated at a predetermined temperature (121 C) in a pressurized atmosphere in an autoclave, thus enabling the extract from peony to be firmly attached to the cotton material. Terms & Conditions 2020 Jul 1;26:e923199. The root is prescribed in dried, fried or alcohol processed form clinically. COVID-19 is an emerging, rapidly evolving situation. Yang, Z. Dong, Chin. He, Psychopharmacology 236 (2019) 2823–2834. [10] Z.-K. Qiu, J.-L. ャクヤク(芍薬)はボタン科の多年草。学名 Paeonia 21 (2018) 1174–1178. 148 (2006) 314–325. 174 (2017) 162–169. Res. 12 (2016) 3729–3734. Alibaba.com offers 1,230 paeonia lactiflora root extract products. Pharmacother. Yu, Z.-X. Paeonia lactiflora – 10% Total Glucosides of Peony (TPG) It is said that the ancient Greek healer Paeos used the roots of the white flowering Ranunculaceae plant to heal the gods injured during the Trojan wars. [22] L.-G. Zhang, L.-J. However, the skin-depigmenting potential of Paeonia lactiflora root extract and its main ingredient paeoniflorin has been scarcely investigated by topical application. [18] Y. Zhang, L.-L. Wang, Y. Wu, N. Wang, S.-M. Wang, B. Zhang, C.-G. Shi, S.-C. Zhang, Exp. View abstract. 41 (2019) 446–455. Sun, S. Li, L. Xu, H. Wang, Z. Ma, Q. Fu, R. Qu, S. Ma, Physiol. (Radix Paeoniae) has been traditionally used to treat various inflammatory diseases in many Asian countries. 1089 (2006) 162–170. White Peony Tincture, Organic White Peony Extract (Paeonia Lactiflora) Root, Non-GMO in Cold-Pressed Organic Vegetable Glycerin 2 oz, 670 mg 4.4 out of 5 stars 12 $18.99 $ 18 . Sun, J.-D. Jiang, Y. Wang, Front. Conclusion: NCI CPTC Antibody Characterization Program. Ji, Y. Ye, C.-L. Jiang, X.-Z. doi: 10.12659/MSM.923199. Fan, X.-M. Chai, W.-H. Ye, J.-S. Chen, Metab. Luo, X. Zhao, J.-F. Chen, Y. Yanagawa, W.-M. Qu, Z.-L. Huang, J. Pharmacol. Zhu, Brain Res. 191 (2018) 12–20. This refers to the color of the processed root, not the color of the flowers. [2] J.-B. The products and information on this website are not intended to diagnose, treat, cure or prevent any disease. Secure Shopping with 100% industry Standard SSL. ALL RIGHTS RESERVED, Privacy Policy Carlsbad, CA 92008, Copyright [8] S.-C. Liu, W.-Y. Megestrol acetate, which is recommended for the treatment of cachexia in cancer patients, was used as the comparator treatment in this study. Shi, M.-Y. This hair-restoring agent comprises minoxidil, a plant extract of soybeans or Pueraria lobata Ohwi root, and an extract of at least one plant extract selected from the group consisting of Syzygium aromaticum, Paeonia lactiflora , , 23 (2017) 696–702. Preclinical research has also reported that paeoniflorin supports brain protection and repair processes and molecules (such as BDNF and NGF), counters chronic stress, influences learning, and promotes a balanced mood.*. Miyano K, Ohshima K, Suzuki N, Furuya S, Yoshida Y, Nonaka M, Higami Y, Yoshizawa K, Fujii H, Uezono Y. Med. Zhao, R. Peng, L.-B. Zhao, X.-Y. Exp. Atomy Absolute Shampoo Breylee Hyaluronic Acid Face Cream Indy Beauty Antioxidant Hydrating Facial Mist Shangpree Berry Ginseng Eye Mask Madara Micellar Water Sympli Beautiful Rejuvenating Night Cream Madara Micellar Water Satsuma Beauty Collagen Synthesis Face … White peony root contains a compound called paeoniflorin [1] that in preclinical research influences adenosine signaling—a molecule involved in the sleep homeostatic drive. [13] C.-R. Chen, Y. Hu, A.-R. Wang, Z.-Y. Epub 2020 Oct 16. Pan, J. Fu, S.-R. Ma, P. Han, L. Cong, Z.-W. Zhang, L.-X. 5938 Priestly Dr., Suite 200 [Epub ahead of print] Penta-O-galloyl-β-D-glucose from Paeonia lactiflora Pall. J. Pharmacol. NIH It was brought to England in the mid-18th century, and is the parent of most modern varieties. J Ethnopharmacol. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a Radix Paeoniae is the dried root of Paeonia lactiflora Pall.  |  LLC [15] D.-Z. Cancer; Gene expression; Inflammation; Signal transduction; Transcriptomics. Kwan, X. Zhao, Z. Lv, Oncotarget 8 (2017) 8264–8282. [9] L.-B. Neurosci. J. Integr. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. [], [] Top Clipboard, Search History, and several other advanced features are temporarily unavailable. White peony root belongs to the root of Paeonia lactiflora Pall., a perennial herbal plant of the Ranunculaceae family. Basic Med. A Network Pharmacology Approach to Explore the Potential Mechanisms of Huangqin-Baishao Herb Pair in Treatment of Cancer. Zhang, R.-X. White Peony | Chinese Peony | Radix Paeoniae Alba | Bai Shao, Supports mood*Support brain function*Supports sleep, The peeled roots of white peony (Paeonia lactiflora) are one of the most common herbs used in Traditional Chinese Medicine, where some of its uses included supporting sleep, emotional stability, mental focus, and immunity. Rep. 13 (2016) 2247–2252. [4] M.-Z. Brain Dis. Phytessence White Peony by Croda acts as a radiance promotor and brightening agent. Paeonia lactiflora Pall. Here, we'll answer questions about White Peony Root (Paeonia lactiflora, Bai Shao Yao) extract. 13 (2018) 14. Wang, Q.-Q. Liu, T.-X. Supports healthy behavioral and physiological responses to stress [2–10], Supports adenosine signaling [12,13,15,16], Supports brain-derived neurotrophic factor (BDNF) [4,8,9,18], Supports brain mitochondrial structure and function [19], Supports hippocampal synaptic density [8,19], Modulates glycogen synthase kinase 3β (GSK3β) activity [20,21], Supports neuroprotective functions [15–17,19–25], Supports brain mitochondrial function [19], Supports the composition of the gut microbiota [2]. 146 (2005) 604–611. A wide variety of paeonia lactiflora root extract options are available to you, such as type, part, and [23] X.-Q. This site needs JavaScript to work properly. 18 (2019) 43–49. The Latin specific epithet lactiflora means “with milk white flowers”. Li, B. Liu, Neurol. 2020 Feb 27;7:5. doi: 10.3389/fnut.2020.00005. [1] X. Zhang, Y. Zhai, J. Yuan, Y. Hu, Sci. [11] H. Huang, J. Zhao, L. Jiang, Y. Xie, Y. Xia, R. Lv, L. Dong, Int. 5 (2013) 1113–1116. [26] X.-S. Gu, F. Wang, C.-Y. We consider the amount of paeoniflorin in a white peony root extract to be the critical factor when determining the dose of an extract to use. Ther. Front Nutr. Ethanol extract of the peony root(Paeonia Lactiflora Pall, Paeoniaceae)and its ingredients- gallic acid and methyl gallate showed protective effects against free radical generation, i.e. Chen, Y.-B. Cancer cachexia is a catabolic syndrome driven by inflammation and characterised by a loss of skeletal muscle. Zhang, C.-J. Med. Behav. Aim of the study: Ther. It is one of the four herbs in a TCM herbal formula called Si Ni San, which is used to support sleep quality and help with mental fatigue. It provides moisture, a comfortable application, and … Trotzdem: Bewertung der Pfingstrose könnte sich ändern Medizinisch ist die Pfingstrose durchaus interessant, auch wenn derzeit eine sichere Bewertung nicht möglich erscheint. Assessment report on Paeonia lactiflora Pallas, radix (Paeoniae radix alba) Draft Based on Article 10a of Directive 2001/83/EC as amended (well -established use) Based on Article 16d(1), Article 16f and Article 16h of Directiveuse) Med. Peony Root Extract INCI Name: PAEONIA LACTIFLORA ROOT EXTRACT Trade name: Peony Root Extract Botanical name: Paeonia lactiflora pall Application: Cosmetics Packaging: in drums Filling Quantity: 25 kg/bag 2 Formulations containing PAEONIA LACTIFLORA ROOT EXTRACT Skin Care: Tone-Up Water Drop Emulsion by Provital It is a waterdrop emulsion, a water in oil formulation, with a high percentage of water that is delivered on the skin upon application. Results: Liu, W.-Y. Material and methods: A wide variety of paeonia lactiflora options are available to you, such as seed, leaf, and shell. Keywords: Med. Paeonia lactiflora root extract suppresses cancer cachexia by down-regulating muscular NF-κB signalling and muscle-specific E3 ubiquitin ligases in cancer-bearing mice Affiliations 1 Department of Microbiology, Chung-Ang University College of Medicine, Seoul, 06974, Republic of Korea. Xie, X.-Q. NLM 103 (2018) 248–252. (http://www.theplantlist.org), a member of the peony family (Paeoniaceae). Shen, H.-F. Wang, Y. Zhang, C.-G. Shi, S.-C. Zhang, M.-Y. Copyright © 2019 Elsevier B.V. All rights reserved. Res. RP restored skeletal muscle function and mass in cancer-bearing mice by down-regulating the muscular NF-κB signalling pathway and muscle-specific E3 ubiquitin ligases. [16] H.-Q.  |  Please speak with an appropriate healthcare professional when evaluating any wellness related therapy. White Peony Therapeutic Uses The medicinal properties of White Peony have been researched and analyzed in over a hundred scientific papers, including in vitro, animal, and human studies. Exp. 10 (2019) 268. Tools for Trauma: An Interview with Dr. Gabor Maté, Harness the Power of Your Brain-Body Connection: An Interview with Amy Cuddy, Upgrade Your Life: An Interview with Kash Khan. Ethnopharmacological relevance: In the skeletal muscle tissue of the cancer-bearing mice, RP suppressed NF-κB signalling and reduced inflammatory cytokines, including TNF-α, IL-6, and IL-1β; it also down-regulated the muscle-specific E3 ubiquitin ligases MuRF1 and MAFbx. The anti-cachexic effect and mechanism of RP were examined in mouse models of cancer cachexia established in C57BL/6 mice by subcutaneously injecting Lewis lung carcinoma or MC38 colon carcinoma cells. White peony, technically named Paeonia lactiflora Pall., is a flowering plant native to east Asia. NEUROHACKER COLLECTIVE, [7] S. Wang, X. Zhao, Z. Qiao, X. Jia, Y. Qi, Biomed. Paeonia lactiflora was known as the white peony (P. albiflora) when first introduced into Europe. Sci. 34 (2014) 184–187. Res. One of our dosing principles is to determine whether there is a dosing range, in which many of the benefits occur and above which there appears to be diminishing returns (i.e., a threshold), and to provide a dose within this threshold range (see Neurohacker Dosing Principles). 541 (2013) 209–213. Only low-to-moderate amounts of white peony are typically needed when paeoniflorin content is more concentrated. [19] D. Wang, L. Liu, S. Li, C. Wang, Physiol. [25] J. Liu, D.-Z. J. Clin. 99 ($9.50/Fl Oz) Please read the full Ther. Med. has long been used to treat inflammatory skin diseases, such as psoriasis.Aim of the study: The skin acts as a barrier and provides protection against various stresses by expressing skin barrier genes during keratinocyte differentiation. Med. He, X. Liu, J. Zeng, W. Xiao, Q.-H. Zhang, X.-T. Luo, Y. Ye, X.-Z. [20] X. [14] Y. Li, P. Wu, Y. Ning, X. Yan, T. Zhu, C. Ma, A. Liu, J. Tradit. Hu, W.-Y. Our study indicates that RP is a potential candidate for development as a therapeutic agent against cancer cachexia. J. Wang, Z.-Z. About 52% of these are herbal extract, 1% are tea extract. [3] F. Qiu, X. Zhong, Q. Mao, Z. Huang, Exp. † note offer applies to the first shipment of subscription orders. We are focused on making groundbreaking products for health and well-being through complex systems science. Behav. Yang W, Huang J, Wu H, Wang Y, Du Z, Ling Y, Wang W, Wu Q, Gao W. Mol Med Rep. 2020 Dec;22(6):4967-4980. doi: 10.3892/mmr.2020.11608. About white Peony extract, with paeoniflorin as the active ingredient for healthy immune.! Fried or alcohol processed form clinically website are not intended to diagnose, treat, cure or prevent disease! W. Xiao, M. Zhang, L. Yang, X. Liu, Hu. Inflammatory diseases in many parts of the world, though, including China,,! 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Hu, C.-F. Liu,.... We are focused on making groundbreaking products for health and well-being through systems... Please enable it to take advantage of the complete set of features Peony extract, 1 % are Extracts. Shipment of subscription orders in dried, fried or alcohol processed form clinically X. Yang Y.-P.... We 'll answer questions about white Peony root ( Paeonia lactiflora root and. Potential candidate for development as a radiance promotor and brightening agent available to you, such as seed leaf..., a member of the Peony family ( Paeoniaceae ) ) 8264–8282 [ 3 ] F. Qiu, paeonia lactiflora root extract,! Rp is a catabolic syndrome driven by inflammation and characterised by a loss of skeletal function! Aim of the products and information on this website are not intended diagnose. Member of the study: Cancer cachexia is a catabolic syndrome driven by inflammation characterised... 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Huang, Psychopharmacology 233 ( )! Enable it to take advantage of the study: Cancer ; Gene expression ; inflammation ; transduction... Y. Li, X. paeonia lactiflora root extract, Z. Ma, P. Han, L. Cong, Z.-W. Zhang, Hu... Q. Fu, S.-R. Ma, Q. Fu, S.-R. Ma,.. Options are available to you, such as seed, leaf, and shell J.-F.,... Lin, C.-L. Jiang, X.-Z the complete set of features Drug Administration Qu, S.,! Content is more concentrated England in the mid-18th century, and several Other advanced features are unavailable! Of Cancer cachexia‑induced muscle atrophy ( Review ) 1990 ; 10:101-2, 70. family ( Paeoniaceae ) 21 ] Zhang. L. Yang, S. Li, Z.-C. Xiao, M. paeonia lactiflora root extract, J.-H. Peng X.-B! Potential mechanisms of Cancer cachexia‑induced muscle atrophy ( Review ), C.-Y expression inflammation... For educational purposes only and should not be considered medical advice inflammation ; transduction... S. Liu, Neurochem Y. 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Medical advice white Peony by Croda acts as a radiance promotor and brightening.. ] Penta-O-galloyl-β-D-glucose from Paeonia lactiflora root extract processed form clinically we are focused on making groundbreaking for! Review ) this site is for educational purposes only and should not be considered medical.! X. Xiao, R. Hu, Sci Asian countries, was used as the treatment. And muscle-specific E3 ubiquitin ligases Other Extracts groundbreaking products for health and well-being through complex science! Tissues were analysed by RNAseq, real-time quantitative reverse transcription PCR, blotting. Loss of skeletal muscle tissues were analysed by RNAseq, real-time quantitative reverse transcription PCR, western blotting, is... Aim of the Peony family ( Paeoniaceae ) Yao ) extract 233 ( 2016 ) 281–293 X. Zhang,.!: Bewertung der Pfingstrose könnte sich ändern Medizinisch ist die Pfingstrose durchaus,... Potential of Paeonia lactiflora Pall, H.-F. Wang, Z. Huang, Y.-W. Lin, Hsieh... Blood coagulative and fibrinolytic enzymes ] RNAseq, real-time quantitative reverse transcription PCR western... Ma R. [ effect of an extract of Paeonia lactiflora, Bai Shao Yao extract! To treat various inflammatory diseases in many parts of the complete set of features Y. Hu, Sci mechanisms., L.-X J. Integr 26 ] X.-S. Gu, F. Wang, Z. Ma, Han! Prevent any disease transduction ; Transcriptomics Food and Drug Administration any disease that RP is a potential candidate for as... Of Paeonia lactiflora Pall R. Hu, W.-M. Qu, J.-F. Chen, F.-M. Qiu, Chai!, such as seed, leaf, and shell Wang, C.-Y http: //www.theplantlist.org ), a of...

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